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Dr. Alpana Mohta Ranka, MD, DNB, IFAAD, is a dual-board-certified dermatologist with over 90 research publications in peer-reviewed scientific journals.


Mesotherapy for Face: The Hottest New Skin Rejuvenation Technology You Haven't Heard Of

Updated: Feb 4

With the rise in non-surgical fat reduction and skin rejuvenation treatments like dermal fillers, microneedling and vampire facials—mesotherapy has begun to gain popularity as well.

Celebrities such as Katy Perry, Madonna, Rihanna and Jennifer Aniston are talking about their love of Mesotherapy—and more people than ever before are taking notice.

What is Mesotherapy?

Mesotherapy is a procedure that uses vitamins, minerals, and proteins to break down fat cells under the skin. It also contains hyaluronic acid—a substance produced naturally by humans—and higher life forms—that protects the structural integrity of your skin.

Mesotherapy is a minimally invasive treatment first pioneered by French doctor Michel Pistor in the 1950s. Although it has been popular for years in western countries, India only recently began catching on with this procedure as more and more people find out about its benefits.

Mesotherapy involves injecting vitamins and minerals through microneedles given into the skin. The injections are carefully crafted and then directly injected into the middle layer of skin, called mesoderm. Depending on what is needed to achieve optimum results (reduce fat, strengthen & firm skin, anti-aging), various ingredients can be included.

The Benefits of Mesotherapy

There are countless things that Mesotherapy can do for you, including smoothing out wrinkles; removing loose skin; erasing cellulite; treating acne scarring to help clear up your face and even lightening dark spots.

Mechanism of Mesotherapy

Mesotherapy uses a combination of vitamins, minerals, amino acids and pharmaceuticals injected into your skin using tiny micro-needles to help reduce wrinkles, remove body fat, and fine lines. It is also used for other purposes like rejuvenating dull-looking skin or treating acne scarring or dark spots.

The ingredients in this formula are micro-needled into the middle layer of your skin. Here they break down fat cells and encourage elimination. This reduces body fat where you want it gone most. They also nourish and rejuvenate the epidermis itself so that all exposed areas maintain a smooth texture with minimized dimpling or creasing from previous stretching marks. Mesotherapy increases elastin in the skin, making skin firm and more elastic.

Ingredients Used in Mesotherapy

There are many different kinds of ingredients that can be used in mesotherapy, depending on the area being treated and what results you’re seeking.

HYALURONIC ACID – A naturally occurring substance that helps the body retain water and keep skin plump by attracting moisture from the atmosphere. Hyaluronic acid also promotes collagen formation, inhibits the aging of cells caused by free radicals, and neutralizes bacteria on the surface of our skin.

VITAMINS & MINERALS—including essential vitamins and minerals such as vitamin A, vitamin B complex, iron and zinc—help keep your skin healthy by protecting it from aging. They also help reduce the signs of aging by fighting off free-radical damage that causes wrinkles!

AMINO ACIDS - These are small organic compounds that combine to make proteins and enzymes used in a variety of ways by the body. Injecting L-Carnitine, for example, can help fat cells transportation and clearance.

ENZYMES such as Deoxycholate are added to burn fat cells so they can penetrate deep into skin cells.

During a Mesotherapy Session

Solutions infused with nutrients are injected into the middle layer of the skin using microneedles. In order to ease the session, your dermatologist might apply a numbing cream prior to the treatment session.

Mesotherapy treatment sessions are typically spaced 2-3 weeks apart and involve several injections administered to areas of the body you wish to target.

The injection Session take about 20-30 minutes and should be comfortable for you throughout.

Post-Mesotherapy Session

The treatment has no downtime. Although, your skin might stay slightly red for the next 1-2 days. Also, just like all good things that take time, mesotherapy also takes 2-6 weeks to show results.

Shelf Life of Results

The results of mesotherapy are often long-lasting and noticeable for 12-18 months after the treatment. A touch-up every 4-6 months is ideal to have sustained results.

Mesotherapy is useful for both face and body contouring, revitalization, and rejuvenation. However, before undergoing a mesotherapy session always seek advise from a certified dermatologist.


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